The Naive State of Human Pluripotent Stem Cells: A Synthesis of Stem...

Cell Stem Cell , Vol. 15, No. 4. , pp. 410-415, doi:10.1016/j.stem.2014.09.014 To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document.

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Cleveland Clinic: Top 10 medical innovations for 2015

The speed of science is often excruciatingly slow. But over the last decade we've made significant strides in medical research, disease treatment and the improvement of patients' quality of life.

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Can scientists patent life? The question returns to the Supreme Court

The thorny and unresolved question of whether life itself can be patented may come again before the U.S. Supreme Court, if it accepts a motion filed Friday by Santa Monica-based Consumer Watchdog. The issue isn't a new one either for the consumer group or the Court.

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Promising New Knee Drug Appears To Regenerate Cartilage

A relatively unknown company called Ampio Pharmaceuticals has been developing a promising new drug used to treat patients suffering from painful and debilitating osteoarthritis of the knee. The drug is called Ampion.

http://ift.tt/1sRoUMM

Breast Cancer Campaign sees Cardiff Devils fans go pink at Panthers clash

... and relapse of breast cancer. Forward Luke Piggott , who works at Cardiff University's European Cancer Stem Cell Research Institute, completed doctor of philosophy studies in cancer research and published a paper on the treatment he discovered. He ...

http://ift.tt/10aTPgi

Five scientists nab awards for high-risk, high-return research

The NIH has announced that Sean Wu will receive a Pioneer Award; Michael Bassik will receive a New Innovator Award; and David Chan, Michael Angelo and Eric Nelson will receive Early Independence Awards. Five scientists at the School of Medicine have received awards totaling $7.75 million to pursue high-risk, high-reward research, the National Institutes of Health announced today.

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Can we predict the future of medicine?

The speed of science is often excruciatingly slow. But over the last decade we've made significant strides in medical research, disease treatment and the improvement of patients' quality of life.

http://ift.tt/1tIt6ng

First Biosimilar Application Kicks Off Legal Battle

In a landmark lawsuit over the first biosimilar application, Amgen is suing Sandoz for unlawfully refusing to follow the patent resolution protocol laid out by the rules of the Biologics Price Competition and Innovation Act of 2009 . According to the rules of BPCIA, Sandoz was required to share with Amgen its 351 biologics license application for filgrastim and its manufacturing processes and dossier for the product within 20 days of FDA's decision to approve the product.

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Capricor Therapeutics, Inc. To Hold Third Quarter 2014 Business...

Capricor Therapeutics, Inc. , a biotechnology company focused on developing novel therapeutics for the treatment of cardiovascular diseases, today announced that Company management will hold a conference call to discuss third quarter 2014 business highlights on Wednesday, November 12, 2014, at 4:30 p.m. ET. On the call, Dr. Linda Marban, Chief Executive Officer, will review Capricor's recent accomplishments, provide an update on the clinical development program of the Company's lead product candidate, CAP-1002, and discuss other Company updates.

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Study of stem cell origins sheds new light

Writing in the journal PLOS Genetics , researchers from Michigan State University describe how they came across important clues about the origins of stem cells from examining critical early life stages of the mammalian embryo. Amy Ralston has identified a possible source of stem cells, which can advance regenerative and fertility research.

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Cell Isolation/Cell Separation Market worth $5.1 Billion by 2019 - New...

... this region can be attributed to various factors including increasing government support for cancer and stem cell research and expanding biotechnology and biopharmaceutical industries in this region. North America dominates the cell isolation market ...

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Identifying the source of stem cells

When most animals begin life, cells immediately begin accepting assignments to become a head, tail or a vital organ. However, mammals, including humans, are special.

http://ift.tt/1wM369L

'Yorkie and Scalloped' - genes that prime stem cells for fighting infection

Two genes not previously linked with the immune system have been shown by University of California-Los Angeles researchers to play a role in directing progenitor stem cells to fight infection. Progenitor cells are described as being the link between stem cells and the "fully differentiated" cells of organs, tissues and the blood system.

http://ift.tt/1ubOcg0

Stem cell therapy for diabetes

... This background may explain why the production of human beta cells has been a principal objective of stem cell research for many years. If unlimited numbers of beta cells could be produced from somewhere then at least the problem of supply would be ...

http://ift.tt/10ElFmi

Rare blood cancer has higher incidence in African-Americans

Although it is a rare blood cancer, Multiple Myeloma is an aggressive and rapidly progressive illness that causes certain white blood cells, normally responsible for combating illnesses, to be overproduced. This proliferation of abnormal cells is known as myeloma cells, and can lead to the growth of tumors that may potentially spread to multiple sites in the body.

http://ift.tt/1sOTyq8

Aging astrocytes lose ability to protect motor neurons, reveal Cedars-Sinai ALS researchers

Cedars-Sinai ALS research shows that aging astrocytes lose the ability to protect motor neurons, which control movement, but replacing old cells with younger ones engineered to restore an important protein may improve neuron survival Lou Gehrig's disease, also known as amyotrophic lateral sclerosis, or ALS, attacks muscle-controlling nerve cells motor neurons in the brain, brainstem and spinal cord, leading to progressive weakness and eventual paralysis of muscles throughout the body. Patients typically survive only three to five years after diagnosis.

http://ift.tt/106Fpyf

Stem cell patent to reach Supreme Court

The U.S. Supreme Court will be asked to intervene over a controversial embryonic stem cell patent, opponents of the patent said Thursday. Jeanne Loring, a stem cell scientist at The Scripps Research Institute, said the court will be asked Friday to overturn a lower court decision and allow the opponents to seek cancellation of the patent held by the Wisconsin Alumni Research Foundation, or WARF.

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Kerry Simon's first MSA conference aims to plan roadmap of research

Kerry Simon and Elizabeth Blau attend the Simon Says Fight MSA benefit at Keep Memory Alive event center Thursday, Feb. 27, 2014, in downtown Las Vegas. The second stage of embattled celebrity chef Kerry Simon's dream to fund research and find a cure for Multiple System Atrophy that has crippled him takes place this weekend as dozens of doctors from across the globe fly here to join officials from the National Institutes of Health.

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Changes in cell metabolism slow growth of colorectal cancer

Cancer is an unwanted experiment in progress. As the disease advances, tumor cells accumulate mutations, eventually arriving at ones that give them the insidious power to grow uncontrollably and spread.

http://ift.tt/1yKPT25

Identifying the source of stem cells

When most animals begin life, cells immediately begin accepting assignments to become a head, tail or a vital organ. However, mammals, including humans, are special.

http://ift.tt/1tnlO77

A 102k for pancreatic cancer research

The money was raised by charity Amser Justin Time and will go to the European Cancer Stem Cell Research Institute, which is a part of Cardiff University. The charity was founded by singer and radio presenter Shan Cothi, whose husband Justin Smith died from the disease in 2007.

http://ift.tt/1wODVGR

The Coming of Age of Stem Cell Therapy

In 2004, the therapeutic potential of stem cells persuaded more than 7 million Californians to approve Proposition 71, which allocated a whopping $3 billion for research and development of stem cell-based drugs and therapies that might someday address a medical dictionary's worth of diseases and conditions. Now, stem cell research is being put to the test in full force as years of cellular and animal studies make the leap to human clinical trials-a requisite step before any new drug or therapy is approved for market.

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Vical Incorporated Reports Third Quarter 2014 Financial Results And...

Vical Incorporated today reported financial results for the three months and nine months ended September 30, 2014. The net loss for the third quarter of 2014 was $4.4 million, or $0.05 per share, compared with a net loss of $9.9 million, or $0.11 per share, for the third quarter of 2013.

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HEMACORDA Wins Prix Galien USA "Best Biotechnology Product" Award

October 30, 2014, New York, NY - The New York Blood Center's Milstein National Cord Blood Program is pleased to announce that HEMACORDA , the first FDA-licensed hematopoietic stem cell product, has been awarded the prestigious "Best Biotechnology Product" Award by Prix Galien USA. The award recognizes "biomedical products that advance the human condition and which were approved by the U.S. Food and Drug Administration during the past five years," according to the Galien Foundation.

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UCLA Gene Discovery Shows How Stem Cells Can Be Activated to Help Immune System Respond to Infection

In a study led by Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research member Dr. Julian Martinez-Agosto, UCLA scientists have shown that two genes not previously known to be involved with the immune system play a crucial role in how progenitor stem cells are activated to fight infection. This discovery lays the groundwork for a better understanding of the role progenitor cells can play in immune system response and could lead to the development of more effective therapies for a wide range of diseases.

http://ift.tt/1whruSs

Tiny Stomachs Grown in the Lab

Part of a miniature stomach grown in the lab, stained to reveal various cells found in normal human stomachs. Credit: Kyle McCracken Scientists have successfully grown miniature stomachs in the lab from human stem cells, guiding them through the stages of development seen in an embryo.

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World-First Embryonic Stem Cell Trial for the Heart

The long-awaited trial comes after much preclinical cell work on more than 350 rats, 50 immunodeficient mice and 32 non-human primates. "After 20 years in the stem cell area and a daily practice of cardiac surgery, I am very cautiously optimistic," Principle Investigator Philippe Menasche told Bioscience Technology .

http://ift.tt/1rWVtKc

Cancer diagnosis prompts music contest to help other cancer patients

Music has the power to heal, to soothe and to relax. So when one woman was diagnosed with cancer she used it to comfort her.

http://m.deseretnews.com/article/865614305/Cancer-diagnosis-prompts-music-contest-to-help-other-cancer-patients.html

UCLA stem cell research may lead to new treatments for many diseases

Researchers affiliated with the UCLA Eli and Edythe Broad Center of Regenerative Medicine have discovered two genes that are involved with the immune system and are related to the functioning of stem cells . Progenitor cells are similar to stem cells because they have a tendency to differentiate into a specific type of cell; however, they are more specific than a stem cell and can be driven to develop into a "target" cell.

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Amy Ralston Biochemistry and Molecular Biology office: (517) 432-8743 aralston

When most animals begin life, cells immediately begin accepting assignments to become a head, tail or a vital organ. However, mammals, including humans, are special.

http://ift.tt/1rWOaC8

Lou Gehrig's disease study: Renewing brain's aging support cells may help neurons survive

Lou Gehrig's disease, also known as amyotrophic lateral sclerosis, or ALS, attacks muscle-controlling nerve cells - motor neurons - in the brain, brainstem and spinal cord. Patients typically survive only three to five years after diagnosis.

http://ift.tt/1FZKLMC

Cancer diagnosis prompts music contest to help other cancer patients

Jenny Ahlstrom was diagnosed with multiple myeloma four years ago. While still in treatment, where she was isolated from family for over seven months, music became her solace.

http://ift.tt/1FZKNE1

UTA researcher uses microscaffolding injections to mend cartilage, prevent osteoarthritis

Liping Tang, professor and interim chair of the bioengineering department at the University of Texas at Arlington, is working on a US Army grant that will use microscaffolding injections to... A UT Arlington bioengineering professor has received a $1.04 million grant from the U.S. Army that aims to regenerate cartilage tissue and reduce osteoarthritis using a patient's own stem cells, spurred through the injection of microscaffolding made of biodegradable polymers. Liping Tang, a bioengineering professor and interim chair of the bioengineering department, said the research is primarily focused on helping soldiers who are severely injured on the battlefield.

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SDLP: Durkan backs 'Save a Life At 16' campaign

SDLP Foyle MP Mark Durkan has supported Anthony Nolan's 'Save a Life At 16' campaign which aims to find teenagers in Derry and throughout the North who will help the charity save the lives of people with blood cancers such as leukaemia. The campaign sees the charity attempt to persuade HMRC to include details of the Anthony Nolan bone marrow donor register when it writes to young people with their National Insurance numbers in advance of their 16th birthdays.

http://www.derryjournal.com/news/sdlp-durkan-backs-save-a-life-at-16-campaign-1-6388061

Reintroducing Protein Complex MPC Slows Colon Cancer Tumor Growth

Therapies that target cancer cells often destabilize the processes that influence the uncontrolled growth of these cells. While some therapies try to eliminate proteins or agents that feed tumors, others rely on introduction of natural cellular agents that have tumor-destroying capabilities.

http://www.medicaldaily.com/reintroducing-protein-complex-mpc-slows-colon-cancer-tumor-growth-308464

Rewiring cell metabolism slows colorectal cancer growth

Many cancers have significantly less mitochondrial pyruvate carrier within them than normal adult cells. Mice were injected either with control colon cancer cells , or colon cancer cells in which mitochondrial pyruvate carrier is re-introduced .

http://ift.tt/1FZmSof

MP supports calls for more young bone marrow donors

The MP is backing Anthony Nolan's 'Save a Life At 16' campaign in a bid to help the charity save the lives of more blood cancer patients. The campaign sees the charity attempt to persuade HMRC to include details of the Anthony Nolan bone marrow donor register when it writes to young people with their National Insurance numbers in advance of their 16th birthdays.

http://ift.tt/1sLcS7C

Lou Gehrig's disease study: Renewing brain's aging support cells may help neurons survive

Cedars-Sinai ALS research shows that aging astrocytes lose the ability to protect motor neurons, which control movement, but replacing old cells with younger ones engineered to restore an important protein may improve neuron survival Lou Gehrig's disease, also known as amyotrophic lateral sclerosis, or ALS, attacks muscle-controlling nerve cells - motor neurons - in the brain, brainstem and spinal cord, leading to progressive weakness and eventual paralysis of muscles throughout the body. Patients typically survive only three to five years after diagnosis.

http://ift.tt/1sLcTZv

Scientists Grow Human Stomach Tissue with Stem Cells

Until now, all stomach studies have been performed on mice, which are less optimal for studying human stomach development and disease. The development comes from labs at Cincinnati Children's Hospital where mini-stomachs were created from a human stem cell.

http://www.myhighplains.com:80/story/d/story/scientists-grow-human-stomach-tissue-with-stem-cel/31171/Ehx2xr3fTEaOC6D5tChiKg

Identifying the source of stem cells

When most animals begin life, cells immediately begin accepting assignments to become a head, tail or a vital organ. However, mammals, including humans, are special.

http://ift.tt/1wIHWsS

Bombing Injury Leads to Stepping Strong Fund, Innovator Award

... body's own stem cells to help muscles heal following traumatic injuries. Major breakthroughs in muscle stem cell research have allowed researchers to isolate muscle stem cells from a small biopsy and help them grow quickly in a laboratory setting. ...

http://ift.tt/1rVNVqX

Reconstruction of a patterned piece of spinal cord in 3D culture

The confocal cross-section of a three-dimensional cyst shows the floor plate , which was formed after the addition of retinoic acid. Furthermore, the development of motor neurons as well as interneurons was shown.

http://ift.tt/1wI0Tgj

Lou Gehrig's disease study: Renewing brain's aging support cells may help neurons survive

Lou Gehrig's disease, also known as amyotrophic lateral sclerosis, or ALS, attacks muscle-controlling nerve cells - motor neurons - in the brain, brainstem and spinal cord, leading to progressive weakness and eventual paralysis of muscles throughout the body. Patients typically survive only three to five years after diagnosis.

http://ift.tt/13k6VKy

Stem-cell research: Having the stomach for it

"Organoids" derived from stem cells help show how embryos develop and why adults get certain diseases. They may even be used as treatments JUST over a year ago, a group of researchers in Austria announced with much fanfare that they had pulled off a spectacular feat of stem-cell science.

http://ift.tt/103DxGd

Lou Gehrig's Disease Study: Renewing Brain's Aging Support Cells May Help Neurons Survive

Lou Gehrig's disease, also known as amyotrophic lateral sclerosis, or ALS, attacks muscle-controlling nerve cells - motor neurons - in the brain, brainstem and spinal cord, leading to progressive weakness and eventual paralysis of muscles throughout the body. Patients typically survive only three to five years after diagnosis.

http://ift.tt/1yJuZ3o

Metabolic requirements for the maintenance of self-renewing stem cells.

To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. A distinctive feature of stem cells is their capacity to self-renew to maintain pluripotency.

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A three-dimensional human neural cell culture model of Alzheimer's disease.

To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. Alzheimer's disease is the most common form of dementia, characterized by two pathological hallmarks: amyloid-I2 plaques and neurofibrillary tangles.

http://ift.tt/1wHXLBd

Scientists build - mini-stomachs' using stem cell

Scientists using stem cells said on Wednesday they had built the world's first "mini-stomachs" - tiny clusters of human gastric tissue that could spur research into cancer, ulcers and diabetes. Called gastric organoids, the lab-dish tissue comprises buds of cells that are "a miniature version of the stomach," the researchers said.

http://ift.tt/1wHXNsN

Development of four early retinal cell types integral to normal vision

University at Buffalo researchers have discovered what regulates generation of the early neurons in the retina during embryonic development. The findings provide clues to how cellular diversity is created in the central nervous system.

http://ift.tt/1tSIQoY

The 'ultimate' stem cell

... Victoria Mascetti concluded that the existence of naive human stem cells required confirmation by other stem cell research groups: "Like Higgs' Boson to the field of particle physics," they explained, naivety in human stem cells "was predicted from ...

http://ift.tt/103afaL

MarketResearch.com: iPSC Research Products Continue 14.7% Annual...

... research products market has grown into existence for iPSCs. According to BioInformant Worldwide, LLC, a stem cell research firm, the number of iPSC research products sold worldwide has been growing at an annual rate of 14.7% for the past five ...

http://ift.tt/1sJUJXR

Mechanism that allows differentiated cell to reactivate as a stem cell revealed

A study, performed with fruit flies, describes a gene that determines whether a specialized cell conserves the capacity to become a stem cell again. Unveiling the genetic traits that favor the retention of stem cell properties is crucial for regenerative medicine.

http://ift.tt/1DBxjKL

Inform your vote: a guide to the 2014 U.S. House of Representatives...

In the race for the House seat of North Carolina's 1st Congressional District, Democrat G.K. Butterfield is seeking a sixth consecutive term against Republican Arthur Rich, who has never held public office. With less than a week until Election Day, take a look at how the candidates match up on key issues.

http://www.dukechronicle.com/articles/2014/10/29/inform-your-vote-guide-2014-us-house-representatives-election

Kiadis Pharma's Lead Product ATIR? Granted Orphan Drug Designation by ...

Kiadis Pharma B.V. , a clinical stage biopharmaceutical company developing T-cell immunotherapy treatments for blood cancers, today announces that its lead product ATIR has been granted Orphan Drug Designation by the European Medicines Agency for the treatment of acute myeloid leukemia . Kiadis Pharma has previously been granted an ODD for ATIR by both the EMA and the FDA for the prevention of acute Graft versus Host Disease following an allogeneic bone marrow transplantation.

http://ift.tt/1zhKB16

Riordan-McKenna Institute Founders, Neil Riordan, PhD and Orthopedic...

On October 26th at the Mid American Regenerative and Cellular Medicine Showcase in Chicago, leading applied stem cell research scientist Neil Riordan, PhD and Orthopedic Surgeon, Dr. Wade McKenna presented talks on New Techniques for Enhancing Stem Cell Therapy Effectiveness and Orthopedic Surgical Applications For Stem Cells. On October 26th at the Mid American Regenerative and Cellular Medicine Showcase in Chicago, leading applied stem cell research scientist Neil Riordan, PhD and Orthopedic Surgeon, Dr. Wade McKenna presented talks on New Techniques for Enhancing Stem Cell Therapy Effectiveness and Orthopedic Surgical Applications For Stem Cells.

http://ift.tt/102xima

Time is right for embryonic research - stem cell expert

... cell projects and can compete internationally, it has made "little contribution" to the area of embryonic stem cell research. "There have been objections on the basis of ethical concerns. But embryonic stem cell research may give rise to other ...

http://ift.tt/1xEEQX5

Billionairesa feud is the bane of Bahamas

New York hedge-fund mogul Louis Bacon won access Wednesday to a trove of video footage that he claims will show his nemesis, Canadian fashion magnate Peter Nygard, orchestrated a smear campaign that falsely painted him as a racist, drug trafficker and murderer. The more than 1,000 hours of footage - recorded by Nygard's former videographer between 2011 and this spring - includes videos with titles like "Is Louis Bacon a Racist?" and "Is Louis Bacon a Murderer?," according to court papers.

http://ift.tt/13gtHmy

Ceo of Parkinson's Institute Shares New Opportunities Regarding Parkinson's Disease

PRLog - Oct. 29, 2014 - RANCHO SANTA FE, Calif. -- Carrolee Barlow, MD, PhD, newly appointed Chief Executive Officer of the Parkinson's Institute and Clinical Center headquartered in Sunnyvale, California, was the featured speaker at a presentation held in Rancho Santa Fe, California, on Wednesday, October 1, 2014.

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See the column...

Diabetes is a disorder in the use of glucose, a sugar that serves as fuel for the body. When blood glucose levels rise, beta cells in the pancreas normally make the hormone insulin.

http://ift.tt/1p3S7tn

A time course analysis of the electrophysiological properties of...

Many protocols have been designed to differentiate human embryonic stem cells and human induced pluripotent stem cells into neurons. Despite the relevance of electrophysiological properties for proper neuronal function, little is known about the evolution over time of important neuronal electrophysiological parameters in iPSC-derived neurons.

http://ift.tt/1q0h1F9

Parkinson's disease induced pluripotent stem cells with triplication of the I -synuclein locus.

A major barrier to research on Parkinson's disease is inaccessibility of diseased tissue for study. One solution is to derive induced pluripotent stem cells from patients and differentiate them into neurons affected by disease.

http://ift.tt/1nRtKOD

Similar Survival Rates in Children with High Risk Blood Cancers...

Children with blood cancer have previously been shown to benefit from umbilical cord blood transplants despite HLA mismatch, making it an important alternative for patients who cannot find a matched unrelated donor. However, the limited number of cells in a single cord blood unit obtained from a placenta after the birth of a child has curbed its potential benefits.

http://ift.tt/1wGN42P

Similar Survival Rates in Children with High Risk Blood Cancers...

Children with blood cancer have previously been shown to benefit from umbilical cord blood transplants despite HLA mismatch, making it an important alternative for patients who cannot find a matched unrelated donor. However, the limited number of cells in a single cord blood unit obtained from a placenta after the birth of a child has curbed its potential benefits.

http://ift.tt/1tDQ1jE

Survival rates in pediatric umbilical cord transplants may indicate a new standard of care

ST. PAUL - A new standard of care for children facing acute myeloid leukemia may be clear, following a multi-year study published in the latest edition of the New England Journal of Medicine . The research, led by John Wagner, Jr., M.D., director of the Pediatric Blood and Marrow Transplantation program at the University of Minnesota and a researcher in the Masonic Cancer Center, University of Minnesota, compared outcomes in children with acute leukemia and myelodysplastic syndrome who received transplants of either one or two units of partially matched cord blood.

http://ift.tt/1sGuJN0

Stem cell advocates therapy launch 10-year, $1.5B action plan

... in Canada in 2013, two-thirds went to treating incurable diseases. "Canada has always been a leader in stem cell research," said Price. "With this action plan and the infrastructure already in place, we have the capacity to transform health care in ...

http://ift.tt/1rT8hkC

Stem cell advocates therapy launch 10-year, $1.5B action plan

... in Canada in 2013, two-thirds went to treating incurable diseases. "Canada has always been a leader in stem cell research," said Price. "With this action plan and the infrastructure already in place, we have the capacity to transform health care in ...

http://ift.tt/1tjAwMk

102914-1030_stem_cell_MS_6.jpg-POS1410291149461129-34902673-1030_stem_cell_MS_6-W.jpg

... in Canada in 2013, two-thirds went to treating incurable diseases. "Canada has always been a leader in stem cell research," said Price. "With this action plan and the infrastructure already in place, we have the capacity to transform health care in ...

http://ift.tt/1DxCYl9

Development of histocompatible primate-induced pluripotent stem cells for neural transplantation.

Immune rejection and risk of tumor formation are perhaps the greatest hurdles in the field of stem cell transplantation. Here, we report the generation of several lines of induced pluripotent stem cells from cynomolgus macaque skin fibroblasts carrying specific major histocompatibility complex haplotypes.

http://ift.tt/1DxCUSq

Where you live doesn't matter if you have heart disease, study finds

People living in rural areas are at no greater risk of dying from heart disease than their urban counterparts, according to a new study. The study, the first to examine outpatient quality of care between urban and rural communities, counters existing research, which suggested gaps in care for those living in rural areas.

http://www.sciencedaily.com/releases/2014/10/141029095448.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fchronic_illness+%28Chronic+Illness+News+--+ScienceDaily%29

Scientific breakthrough in Cincinnati could help battle cancer, ulcers

"Up until now, there's been no good way to study stomach diseases in humans," said James Wells, director of the Pluripotent Stem Cell Facility at Cincinnati Children's Hospital Medical Center.

http://ift.tt/1thNb3O

Cellular alchemy turns skin cells into brain cells

MOVE over stem cells. A new kind of cellular alchemy may allow cells to be converted into other tissues to treat injuries.

http://ift.tt/1p2fZ0j

Campaign for bone marrow donors in Chester

THERE are 818 registered bone marrow donors in Chester but more need to step forward to help save the lives of blood cancer patients. This is the message from the Anthony Nolan Charity, which is urging the Government to include details of the bone marrow register when it writes to young people with their National Insurance numbers ahead of their 16th birthdays.

http://ift.tt/1thN8VM

Tiny human stomachs grown in the lab

Scientists have successfully grown miniature stomachs in the lab from human stem cells, guiding them through the stages of development seen in an embryo. The lumps of living tissue, which are no bigger than a sesame seed, have a gland structure that is similar to human stomachs and can even harbour gut bacteria.

http://ift.tt/1thN8VH

Medical groups call for major stem cell investment from public, private sector

A coalition of Canadian stem cell advocates, researchers and charities is calling for $1.5 billion in private and public funding for stem cell therapy over the next 10 years. The coalition's action plan is aimed at cementing Canada's reputation as a stem cell leader, one that uses stem cell science to reduce suffering and death from cardiovascular diseases, cancer, diabetes, vision loss, spinal cord injuries and other conditions.

http://ift.tt/1Dx6PKr

Mum desperately searching for drug she believes will cure her brain cancer

Donna McWhinnie is desperately seeking someone to supply her with cannabis oil, which she believes will cure her brain cancer A brave young mum fighting brain cancer has made an emotional plea to the public to try and help save her life. Mum-of-one Donna McWhinnie is seeking someone to supply her with cannabis oil , which she believes will cure her.

http://ift.tt/13dakL0

Medical groups call for major stem cell investment from public, private sector

A coalition of Canadian stem cell advocates, researchers and charities is calling for $1.5 billion in private and public funding for stem cell therapy over the next 10 years. The coalition's action plan is aimed at cementing Canada's reputation as a stem cell leader, one that uses stem cell science to reduce suffering and death from cardiovascular diseases, cancer, diabetes, vision loss, spinal cord injuries and other conditions.

http://www.weyburnreview.com/article/GB/20141029/CP02/310299912/-1/weyburn/medical-groups-call-for-major-stem-cell-investment-from-public&template=cpart

Five scientists nab awards for high-risk, high-return research

The NIH has announced that Sean Wu will receive a Pioneer Award; Michael Bassik will receive a New Innovator Award; and David Chan, Michael Angelo and Eric Nelson will receive Early Independence Awards. Five scientists at the School of Medicine have received awards totaling $7.75 million to pursue high-risk, high-reward research, the National Institutes of Health announced today.

http://ift.tt/1s5cd6J

Imaging the genome: Cataloguing fundamental processes of life

A new study has allowed researchers to peer into unexplored regions of the genome and understand for the first time the role played by more than 250 genes key to cell growth and development. Cells with damage in their DNA assemble abnormally stable microtubule structures .

http://ift.tt/1vh3fQ9

Cellular alchemy turns skin cells into brain cells

Move over stem cells. A different kind of cellular alchemy is allowing cells to be converted directly into other tissues to treat disease or mend injuries.

http://ift.tt/1pYSm3D

Call for stem cell investment

A coalition of Canadian stem cell advocates, researchers and charities is calling for $1.5 billion in private and public funding for stem cell therapy over the next 10 years. The coalition's action plan is aimed at cementing Canada's reputation as a stem cell leader, one that uses stem cell science to reduce suffering and death from cardiovascular diseases, cancer, diabetes, vision loss, spinal cord injuries and other conditions.

http://ift.tt/13cCy8z

A mechanism that allows a differentiated cell to reactivate as a stem cell revealed

The study, performed with fruit flies, describes a gene that determines whether a specialized cell conserves the capacity to become a stem cell again One kind of stem cell, those referred to as 'facultative', form part - together with other cells - of tissues and organs. There is apparently nothing that differentiates these cells from the others.

http://ift.tt/1E1VDra

Medical groups call for major stem cell investment from public, private sector

A coalition of Canadian stem cell advocates, researchers and charities is calling for $1.5 billion in private and public funding for stem cell therapy over the next 10 years. The coalition's action plan is aimed at cementing Canada's reputation as a stem cell leader, one that uses stem cell science to reduce suffering and death from cardiovascular diseases, cancer, diabetes, vision loss, spinal cord injuries and other conditions.

http://ift.tt/13cplgb

The diagnosis and treatment of dyskeratosis congenita: a review.

To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. Dyskeratosis congenita is an inherited bone marrow failure syndrome characterized by the classic triad of abnormal skin pigmentation, nail dystrophy, and oral leukoplakia.

http://ift.tt/13cpn7y

BioTime: Recent News Hints At Positive Developments

... IND is the culmination of 12 years of research and development starting at the Hadassah Human Embryonic Stem Cell Research Center at Hadassah University Medical Center, Jerusalem, Israel, under the direction of Prof. Benjamin Reubinoff, MD, PhD and ...

http://ift.tt/13cfBm8

Medical groups call for major stem cell investment from public, private sector

A coalition of Canadian stem cell advocates, researchers and charities is calling for $1.5 billion in private and public funding for stem cell therapy over the next 10 years. The coalition's action plan is aimed at cementing Canada's reputation as a stem cell leader, one that uses stem cell science to reduce suffering and death from cardiovascular diseases, cancer, diabetes, vision loss, spinal cord injuries and other conditions.

http://ift.tt/13cfxTl

ViaCyte's VC-01? Investigational Stem Cell-Derived Islet Replacement...

... ance leading-edge stem cell medicine and science, protect and counsel patients, and accelerate innovative stem cell research into patient diagnostics and therapies.

http://ift.tt/1E1RtzN

Coalition calls on Ottawa to commit $500 million for stem cell research

A coalition of prominent scientists, entrepreneurs and charities is calling on Ottawa to commit half a billion dollars over the next 10 years to boost stem cell research and development in Canada. The request to the federal government works out to one-third of the $1.5-billion in private and public funding the group says this country needs to remain at or near the top of a field that two Canadian scientists helped found with their discovery of adult stem cells in the early 1960s.

http://ift.tt/1rzZG5v

The 'ultimate' stem cell

... Victoria Mascetti concluded that the existence of naive human stem cells required confirmation by other stem cell research groups: "Like Higgs' Boson to the field of particle physics," they explained, naivety in human stem cells "was predicted from ...

http://ift.tt/1E1AwFB

JDRF-Funded Islet Encapsulation Program Reaches Historic Milestone

... new and effective treatment for type 1 diabetes. This day would not have been possible without the basic stem cell research and the insights learned to protect insulin-producing cells from the autoimmune attack that JDRF has been funding for years." ...

http://www.freshnews.com/news/1006574/jdrf-funded-islet-encapsulation-program-reaches-historic-milestone

Scientist of the year award for Duchenne Muscular Dystrophy research

Professor Dickson, School of Biological Sciences at Royal Holloway, University of London, is presented with his award by Sue Barker. The School of Biological Sciences at Royal Holloway, University of London has been recognised with a national award for its world-class research in the development of novel therapies for rare diseases, such as Duchenne Muscular Dystrophy .

http://ift.tt/1wCSquW

FDA Grants Kamada Orphan Drug Designation for the Treatment of Graft versus Host Disease

Kamada Ltd. , a plasma-derived protein therapeutics company focused on orphan indications, announces that the U.S. Food and Drug Administration's Office of Orphan Products Development has granted orphan drug designation for GlassiaA , the Company's proprietary human Alpha-1 Antitrypsin , to treat Graft-versus-host-disease . Orphan drug designation carries multiple benefits, including the availability of grant money, certain tax credits and seven years of market exclusivity, as well as the possibility of an expedited regulatory process.

http://ift.tt/1zJh1Tx

FDA Grants Kamada Orphan Drug Designation for the Treatment of Graft versus Host Disease

Kamada Ltd. , a plasma-derived protein therapeutics company focused on orphan indications, announces that the U.S. Food and Drug Administration's Office of Orphan Products Development has granted orphan drug designation for GlassiaA , the Company's proprietary human Alpha-1 Antitrypsin , to treat Graft-versus-host-disease . Orphan drug designation carries multiple benefits, including the availability of grant money, certain tax credits and seven years of market exclusivity, as well as the possibility of an expedited regulatory process.

http://ift.tt/1p0PDf8

Discovery of how newborn mice repair bone fractures could improve treatments

Severe fractures in infants can heal on their own through a process that has eluded scientists. A study now reveals that a fractured arm bone in newborn mice can rapidly realign through a previously unknown mechanism involving bone growth and muscle contraction.

http://ift.tt/1thxMzc

The Irvine Stem Cell Treatment Center Announces Adult Stem Cell...

The Irvine Stem Cell Treatment Center announces a series of free public seminars on the use of adult stem cells for various chronic, degenerative and inflammatory conditions. They will be provided by Dr. Thomas A. Gionis, Surgeon-in-Chief.

http://ift.tt/1venRs6

The Miracle of Stem Cell Therapy at Adler Footcare Regenerates Cells,...

Backed by years of research, thousands of happy patients, and faster healing time is the latest in ethical stem cell treatments for foot pain offered at Adler Footcare of Greater New York. Stem cell therapy stimulates and produces healthy bones and cartilage to repair what's been damaged in the foot and causing people debilitating foot pain.

http://ift.tt/1sD1gUi

UWA scientist Ryan Lister wins Prime Minister's prize for life science

A scientist from the University of WA says he is humbled to be awarded the Prime Minister's prize for life science. Professor Ryan Lister researches epigenomes - the chemical compounds surrounding DNA - and is one of six people to receive a prize for science from Prime Minister Tony Abbott in Canberra.

http://ift.tt/1tJHo8w

Cancer diagnosis prompts 'Songs for Life'

There are many labels that define Jenny Ahlstrom: wife, mother, musician and entrepreneur are a few of them. But one label she won't let control her is cancer patient.

http://ift.tt/1zH7Oeq

Ancient India: Been there, invented that

One has to say, this is the best time ever to be an Indian. Not counting, of course, how good it was 7,000,000 years ago, mainly because I can't remember those days quite so well.

http://ift.tt/1DZdFKP

Gene therapy, stem cell therapy trials underway

Stem cells and gene hold promising treatment options for Parkinson's, mandate doctors across the globe, including from Mumbai. Eleven trials to test stem cell and gene therapy for treating Parkinson's are underway currently of which the one in Mumbai had to be put on hold due to regulatory hurdles.

http://ift.tt/1wAVEz1

Caribbean International Holdings, Inc. (CIHN) Announces New...

... bringing science and medicine together to improve the well-being and future of patients. His knowledge in stem cell research and development as well as implementing standard operating procedures will be a tremendous benefit to our Company. In ...

http://ift.tt/1rynJ4L

Prevention of lysosomal storage diseases and derivation of mutant...

To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document. Preimplantation genetic diagnosis allows birth of unaffected children for couples at risk for a genetic disorder.

http://ift.tt/1DsdIwu

Colorado Doctors Herald Diabetes Research Breakthrough

Diabetes researchers are celebrating a major scientific breakthrough that could be a step toward a cure for Type 1 diabetes. "All of us would hope that Type 1 diabetes would be cured some day and despite all the good efforts by many bright scientists, we haven't seen a cure.

http://ift.tt/1oWtgYq

"Occlusive Coronary Artery Disease Global Clinical Trials Review, H2, ...

... Medisch Centrum Utrecht Clinical Trial Overview of Universitair Medisch Centrum Utrecht Adult Stem Cell Research Center Clinical Trial Overview of Adult Stem Cell Research Center North Texas Veterans Healthcare System Clinical Trial Overview of ...

http://reports.pr-inside.com/occlusive-coronary-artery-disease-global-r4145541.htm

Banging the Drum on Science When It Fits Your Tune

Scientists, who have come to rely on liberals in political battles over stem-cell research, climate change and the teaching of evolution, have been dismayed to find themselves at odds with their traditional allies on this issue . Some compare the hostility to G.M.O.s to the rejection of climate-change science, except with liberal opponents instead of conservative ones.

http://ift.tt/1rxUFtW

Former Google exec's app offers 24/7 health coaching

As a growing number of startups use technology to more immediately connect people to health care services , a former Google executive is launching a mobile app that gives users "health coaching" at the push of a button. Vida said Tuesday that it has raised $5 million for its app, which gives users 24/7 access to a nationwide network of health coaches and providers via phone calls, text messages and video conferencing.

http://ift.tt/1u4dJrp

Current and emerging strategies for the prevention of graft-versus-host disease.

Graft-versus-host disease represents the most serious and challenging complication of allogeneic haematopoietic stem-cell transplantation . New insights on the role of regulatory T-cells, T cells, and antigen-presenting cells have led to an improved understanding of the pathophysiology of GVHD.

http://www.citeulike.org/user/jrifon/article/13411336

Banging the Drum on Science When It Fits Your Tune

Scientists, who have come to rely on liberals in political battles over stem-cell research, climate change and the teaching of evolution, have been dismayed to find themselves at odds with their traditional allies on this issue . Some compare the hostility to G.M.O.s to the rejection of climate-change science, except with liberal opponents instead of conservative ones.

http://blogs.discovermagazine.com/collideascape/2014/10/28/banging-drum-science-fits-tune/?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A%20DiscoverMag%20%28Discover%20Magazine%29

Daily Business Report-Oct. 28, 2014

... Boosting Possibility Through Innovation and Entrepreneurship" will also focus on latest advances in stem cell research, nanotechnology and other medical applications and how to market to millennials, as well as how to do business in America and ...

http://www.sandiegometro.com/2014/10/daily-business-report-oct-28-2014-2/

Brave Margot Martini loses leukaemia fight but inspires thousands to become bone marrow donors

Henny Braund, chief executive of the Anthony Nolan Trust heaped praise on the brave two-year-old after she lost her battle with the disease The boss of the Anthony Nolan Trust paid tribute to Margot Martini and revealed how the brave toddler inspired "tens of thousands of people" to join the register. The courageous two-year-old lost her battle against leukaemia yesterday morning, with loving parents Yaser and Vicki and her family by her side.

http://ift.tt/1tf5Jlt

Juventas Therapeutics, Inc. Strengthens Management Team With New...

Troy brings 20 years in finance, operations, and business development experience with start-up and established life sciences companies. Mr. Ignelzi joins Juventas from YES Pharmaceuticals where he was Sr. Vice President of Business Development.

http://ift.tt/1vaHPUQ

Penn to explore 'Women in Science' at symposium

Former Princeton University President Shirley Tilghman will be among the speakers at Penn's "Women in Science" symposium on Oct. 29. The event, organized by the department of cell and developmental biology at Penn's Perelman School of Medicine, will feature an "all-female panel of luminiaries" in fields such as epigenetics - the study of gene changes not caused by changes in a person's DNA sequencing- and stem cell biology. The program will begin at 1 p.m. with a presentation by keynote speaker, Nobel Laureate Christiane NA1 4sslein-Volhard, who will discuss the development of color patterns in different fish species.

http://ift.tt/1vaohzQ

Juventas Therapeutics Strengthens Management Team with New Senior...

Juventas Therapeutics, a privately-held, clinical-stage company developing novel regenerative therapies for treatment of cardiovascular disease announced today that Troy Ignelzi has joined the company as Senior Vice President of Finance and Operations. Troy brings 20 years in finance, operations, and business development experience with start-up and established life sciences companies.

http://ift.tt/1325zDS

My Pet World: Stem cell treatments show promise for some feline health issues

Q: You recently wrote about stem cell research, and I understand that stem cell therapy is being used to treat inflammatory bowel disease in cats. Do you have more details? A: The Winn Feline Foundation has funded the research of Dr. Craig Webb and Dr. Tracy Webb of Colorado State University College of Veterinary Medicine to study the use of stem cells to treat inflammatory bowel disease in cats.

http://ift.tt/131XUFP

Challenges in Using Old Tissue and Cells in Treatments

... aging is there, however, and other uses for a patient's own tissues are indeed impacted. This is why the stem cell research field is on a trajectory to understand and reverse aspects of aging in old tissues; they have to do this in order to ensure ...

http://ift.tt/1oUYBum

Cellular Dynamics receives contract to make eye cells

The cells, which the Madison-based company will create using pluripotent stem cell technology to reprogram blood and skin samples, will be part of an effort to fight macular degeneration, a condition that leads to loss of vision. The cells can be implanted into a patient's eyes to treat the disorder.

http://ift.tt/130Rjve

Anti-cancer drug effective against common stem cell transplant complication

The drug bortezomib effectively treats chronic graft-versus-host disease , a common and debilitating side effect from allogeneic hematopoietic stem cell transplants, a study has found. The trial showed that bortezomib provides better outcomes than existing treatments and does not impair the immune response against residual cancer cells, or the graft-versus-tumor effect .

http://www.sciencedaily.com/releases/2014/10/141025215651.htm?utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+sciencedaily%2Fhealth_medicine%2Fcancer+%28Cancer+News+--+ScienceDaily%29

Community mourns death of brave Caiden

The local community and farther afield has been deeply saddened by the death at the weekend of brave Ballymena boy Caiden Tang. The six-year-old lost his long fight against cancer on Saturday when he passed away peacefully at hospital in Belfast.

http://ift.tt/1tDJneA

It takes just a week to grow a blood vessel

The technology for creating new tissues from stem cells has taken a giant leap forward. Two tablespoons of blood are all that is needed to grow a brand new blood vessel in just seven days.

http://ift.tt/ZVz3RW

Immorality and invention: the "great stem cell debate"

Human stem cell research holds promise for combating some of the most recalcitrant of diseases and for regenerating damaged bodies. It is also an ethical, legal and political minefield.

http://ift.tt/ZVD2y8

Beverly Hills Stem Cell Clinic with Dr. Raj Now Replacing Knee...

Dr. Raj of the Beverly Hills Orthopedic Institute is now offering stem cell procedures which can help replace knee cartilage. The procedures are outpatient, low risk and highly effective at providing pain relief.

http://ift.tt/1oU6UH3

Toxin-secreting stem cells engineered to treat brain tumors

Harvard Stem Cell Institute scientists at Massachusetts General Hospital have devised a new way to use stem cells in the fight against brain cancer . A team led by neuroscientist Khalid Shah, MS, PhD, who recently demonstrated the value of stem cells loaded with cancer-killing herpes viruses, now has a way to genetically engineer stem cells so that they can produce and secrete tumor-killing toxins.

http://ift.tt/1DVwrTd

Woman with Lymphoma Saved by Adult Stem Cell Research

Here is another story in which stem cell research using Adult Stem Cells played the star role. Kim Case, a woman from Gaston, Oregon was given little hope to live after being diagnosed with NK T-cell Lymphoma.

http://ift.tt/1wGSlsE

MP backs charity's calls for more bone-marrow donors

The MP is backing a campaign from the Anthony Nolan charity to encourage more bone-marrow or stem-cell donors to come forward and offer to save the life of a stranger fighting blood cancer. There are 462 people in the Wansbeck constituency who have joined the charity's register, but the average number of potential donors in Parliamentary constituencies is 819.

http://ift.tt/1u27zYK

ASC Helps English Woman with Congestive Heart Failure

Barbro Lowed, a retired air hostess from London, England says that stem cell research using Adult Stem Cells removed from her bone marrow has given her her life back. Barbro had previously been suffering from congestive heart failure.

http://ift.tt/1te9VBQ

Toxin-producing stem cells fight brain tumors where it matters most

Encapsulated toxin-producing stem cells help kill brain tumor cells in the tumor resection cavity When it comes to new tumor-fighting treatments, it's often as much about location, location, location as it is the actual drug interaction. Cytoxin-producing stem cells produced by scientists at Harvard University lodge at the site of brain tumor removal to continually attack remaining tumor cells.

http://ift.tt/1wG372c

Golf tournament helps Carson City woman

A golf tournament fundraiser is planned on Nov. 23 at Thunder Canyon County Club for Carson City's Christy Joyce, who was diagnosed with multiple myeloma and will undergo a stem cell replacement procedure at Stanford Health Care. The cost, which includes golf and lunch, is $125 per person or $450 for a team of four.

http://ift.tt/1DnioUp

Five scientists nab awards for high-risk, high-return research

The NIH has announced that Sean Wu will receive a Pioneer Award; Michael Bassik will receive a New Innovator Award; and David Chan, Michael Angelo and Eric Nelson will receive Early Independence Awards. Five scientists at the School of Medicine have received awards totaling $7.75 million to pursue high-risk, high-reward research, the National Institutes of Health announced today.

http://ift.tt/1s5cd6J

Scientists engineer toxin-secreting stem cells to treat brain tumors

Harvard Stem Cell Institute scientists at Massachusetts General Hospital have devised a new way to use stem cells in the fight against brain cancer. A team led by neuroscientist Khalid Shah, MS, PhD , who recently demonstrated the value of stem cells loaded with cancer-killing herpes viruses , now has a way to genetically engineer stem cells so that they can produce and secrete tumor-killing toxins.

http://ift.tt/1oSuRhR

Vida Miller For SC House District 108

The citizens of S.C. House District 108 - a lengthy stretch of the South Carolina coastline running through Charleston and Georgetown Counties - were fortunate to have had a real citizen leader as their representative from 2011-13. Sure we made fun of him a bit , but former S.C. Rep. Kevin Ryan voted way better than the vast majority of Democrats and "Republicans" in the S.C. House.

http://ift.tt/1zBAPYY

'Light The Night Walk' Team Participates In Memory Of Peekskill Man

Marion Clark's son Jeffrey Clark, Jr., a Peekskill resident, was only 23 years old when he died after a three year battle with non-Hodgkins lymphoma. Marion Clark, who now lives in Harrison, will be participating in the Leukemia and Lymphona Society's Light The Night Walk at Playland Amuesement Park In Rye on Saturday, Nov. 1, at 5 p.m. with her team, Jeffrey Lived Loved Laughed.

http://ift.tt/1tAIlzM

RMSR Training Program New Partnership Aims to Help Applicants Obtain Career Certification

... reps." a Genetics a Genetic Engineering a Gene Splicing a Therapeutic Proteins a Monoclonal Antibodies a Stem Cell Research a Transplants, Prosthetics, & Implants a Joint Replacements a Prosthetic Limbs a Implantable Nerve Stimulators a Advances in ...

http://ift.tt/1zBssfM

UC Davis Researchers Find Promising New Treatment Approach for Ischemic Stroke

A team of UC Davis scientists has found that administering a small molecule - purmorphamine - in animal models after a stroke results in multiple protective effects, including reducing the size of the stroke, decreasing inflammation and increasing markers for nerve regeneration. The findings, which may offer a new approach to treating ischemic stroke - the disruption of blood flow in the brain from a blood clot - are published online in the journal Cell Death and Disease .

http://ift.tt/12Uf9bP

UCLA and UCI awarded $8 million grant to launch collaborative stem cell clinic

The UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and UC Irvine Sue and Bill Gross Stem Cell Research Center received a five-year $8 million grant from the California Institute of Regenerative Medicine, the state's stem cell agency, to establish a CIRM Alpha Stem Cell Clinic "center of excellence" to conduct clinical trials for investigational stem cell therapies and provide critical resources and expertise in clinical research. The grant was one of three awarded this week as part of the CIRM Alpha Stem Cell Clinics Network Initiative.

http://ift.tt/1DTuxT7

Clontech Laboratories, Inc. Licenses CRISPR/Cas9 Technology From The Broad Institute

Clontech Laboratories, Inc., a wholly-owned subsidiary of Takara Bio Inc., today announced that they have entered into a non-exclusive license agreement with the Broad Institute to access intellectual property related to the CRISPR/Cas9 gene editing system. "Clontech is pleased to be able to provide innovative tools for CRISPR/Cas9 gene editing under our Guide-it brand," commented Carol Lou, General Manager of Clontech Laboratories, Inc. "We believe that CRISPR/Cas9 technology represents a significant improvement over existing genome editing tools, reaching a new level of targeting, efficiency, and in particular ease of use.

http://ift.tt/ZTBKUh

City of Hope Announces New Hematologic Malignancies and Stem Cell Transplantation Institute

A world leader in the treatment of blood cancers, City of Hope is now launching an institute specifically focused on understanding and treating people with lymphoma, leukemia and myeloma, as well as other serious blood and bone marrow diseases. Through this institute, laboratory and physician investigators will expand their work and develop new therapies and possible cures for leukemia, lymphoma and multiple myeloma.

http://ift.tt/12SpdlI

The effect of standard and high-fluence corneal cross-linking (CXL) on cornea and limbus.

When treating peripheral ectatic disease-like pellucid marginal degeneration , corneal cross-linking with UV-A and riboflavin must be applied eccentrically to the periphery of the lower cornea, partly irradiating the corneal limbus. Here, we investigated the effect of standard and double-standard fluence corneal cross-linking with riboflavin and UV-A on cornea and corneal limbus in the rabbit eye in vivo.

http://ift.tt/1xw9jXk

Clontech Laboratories, Inc. Licenses CRISPR/Cas9 Technology From The Broad Institute

"Clontech is pleased to be able to provide innovative tools for CRISPR/Cas9 gene editing under our Guide-it brand," commented , General Manager of Clontech Laboratories, Inc. "We believe that CRISPR/Cas9 technology represents a significant improvement over existing genome editing tools, reaching a new level of targeting, efficiency, and in particular ease of use. It is destined to become as valuable and widely utilized as RNAi; perhaps more so."

http://www.biospace.com/news_story.aspx?StoryID=351639&full=1

China Independent Clinical Laboratory Market Size 2014, Industry...

MarketResearchReports.Biz include new market research report" China Independent Clinical Laboratory Industry Report, 2014-2017" to its huge collection of research reports. Browse All Biotechnology Market Research Reports at The independent clinical laboratory industry starts relatively late in China, featuring a limited overall size but high-speed development.

http://ift.tt/12RFN58

Cloning whistleblower: Little changed in S. Korea

The whistleblower who exposed breakthrough cloning research as a devastating fake says South Korea is still dominated by the values that allowed science fraudster Hwang Woo-suk to become an almost untouchable national hero. In an interview with The Associated Press after almost a decade of silence, Ryu Young-joon, one of Hwang's former researchers, said the cost of telling the truth still weighs on him but he doesn't regret his decision to out Hwang as a false prophet.

http://ift.tt/1wBVslB

Canadian Stem Cell Experts Gather For Till-McCulloch 2014

... (Photo credit: Wikipedia) Also on the agenda for discussion and debate will be the societal impact of stem cell research, including approaches in moving research towards clinical treatments for patients and the investigation of cancer stem cells and ...

http://ift.tt/ZTDRak

Stem cells that release cancer-killing toxins offer new brain tumor treatment

A new way to to use stem cells to fight brain cancer is revealed in a proof-of-concept study published in the journal Stem Cells , where scientists describe how they got the cells to produce and release toxins that kill only tumor cells. The researchers genetically engineered stem cells to make and secrete toxins that kill brain cancer cells without themselves being affected.

http://ift.tt/1tx0IWv

Numerical integration of a mathematical model of hematopoietic stem cell dynamics

Computers & Mathematics with Applications , Vol. 56, No. 3. , pp. 594-606, doi:10.1016/j.camwa.2008.01.003 To insert individual citation into a bibliography in a word-processor, select your preferred citation style below and drag-and-drop it into the document.

http://ift.tt/1txvNcH

Bortezomib drug effective against chronic GVHD

Researchers at UC Davis have found that the drug bortezomib effectively treats chronic graft-versus-host disease , a common and debilitating side effect from allogeneic hematopoietic stem cell transplants. The trial showed that bortezomib provides better outcomes than existing treatments and does not impair the immune response against residual cancer cells, or the graft-versus-tumor effect .

http://ift.tt/1yFzITD

Actinium Announces Collaboration With Albert Einstein College of Medicine on New Actinium Program

The first antibody to be labeled using the new technology has potential to be broadly used in the field of hematology/oncology. Preclinical studies of the new technology have demonstrated significant improvements in product's manufacturing while maintaining biological integrity and properties of labeled antibodies.

http://ift.tt/1zzl7NL

Celladon Corporation Announces Publication of Data From Its Stem Cell ...

... School of Medicine at Mount Sinai and the Arthur & Janet C. Ross Professor of Medicine at Mount Sinai. Stem cell research has demonstrated potential to treat a variety of diseases. Stem Cell Factor exists in both soluble and membrane bound forms. ...

http://ift.tt/1stEs9r

Scientists devise novel way to use stem cells in fight against brain cancer

Harvard Stem Cell Institute scientists at Massachusetts General Hospital have devised a new way to use stem cells in the fight against brain cancer. A team led by neuroscientist Khalid Shah, MS, PhD, who recently demonstrated the value of stem cells loaded with cancer-killing herpes viruses, now has a way to genetically engineer stem cells so that they can produce and secrete tumor-killing toxins.

http://ift.tt/1xuzbTq

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AN INSPIRATION TO US ALL: More than 70,000 tributes have already been paid to brave eight-year-old Claudia Burkill. TRIBUTES have flooded in over the weekend to Grimsby-born Claudia Burkill, who has tragically lost her brave fight against cancer.

http://ift.tt/1tca0G9

Global Stem Cells Group Announces Launch of Official Regenestem Network Website

... Cells Group, Inc. is the parent company of six wholly owned operating companies dedicated entirely to stem cell research, training, products and solutions. Founded in 2012, the company combines dedicated researchers, physician and patient educators ...

http://ift.tt/1rJlSem

UC San Diego Named Stem Cell "Alpha Clinic"

... accomplish." The alpha clinic grant reflects continued CIRM support for UC San Diego's well-established stem cell research and development programs. Since it was created in 2004, CIRM has approved 74 awards totaling almost $156 million to UC San ...

http://ift.tt/1wzIpBh

Promise Put to the Test

... beginning to emerge around the country, Goldstein noted that San Diego continues to assert itself as a stem cell research hub and a leading force for translating basic discoveries into medical applications, now and in the future. "These innovative ...

http://ift.tt/1yDWjju

Scientists discover protein that can accelerate cancer patients'...

... said Chute, who also is a member of the UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research. "By modeling it for potential use in human patients, this opens the door for tremendous therapeutic possibilities." Chute and ...

http://ift.tt/1zcZORe

Global and Stage Specific Patterns of KrA1 4ppel-Associated-Box Zinc...

Highly coordinated transcription networks orchestrate the self-renewal of pluripotent stem cell and the earliest steps of mammalian development. KRAB-containing zinc finger proteins represent the largest group of transcription factors encoded by the genomes of higher vertebrates including mice and humans.

http://ift.tt/1rH0BSD

How a tumor suppressor helps control changes in cell shape and...

Ludwig Oxford researchers have discovered a key mechanism that governs how cells of the epithelia, the soft lining of inner body cavities, shift between a rigid, highly structured and immobile state and a flexible and motile form. Published in the current issue of Nature Cell Biology , their study shows that a tumor suppressor protein named ASPP2 functions as a molecular switch that controls this process and its reverse, both of which play a critical role in a number of biological phenomena, including wound healing, embryonic development and, not least, the metastasis of cancers.

http://ift.tt/1tsV1J9

Cloning whistleblower: Little changed in S. Korea

5, 2014 photo, Ryu Young-joon speaks during an interview at Kangwon National University Hospital in Cuncheon, South Korea. . In this Sept.

http://ift.tt/1oH3aZn

Epigenetic Landscapes Explain Partially Reprogrammed Cells and Identify Key Reprogramming Genes

A common metaphor for describing development is a rugged "epigenetic landscape" where cell fates are represented as attracting valleys resulting from a complex regulatory network. Here, we introduce a framework for explicitly constructing epigenetic landscapes that combines genomic data with techniques from spin-glass physics.

http://ift.tt/1yCwyQD

Scleroderma patients seek experimental U.S. stem cell therapy

An estimated 16,000 Canadians live with scleroderma, an incurable autoimmune disorder which causes the body to produce too much collagen, resulting in a hardening of the skin and tissue. There is no cure for the scleroderma, but some patients in Canada are now seeking a costly and experimental stem cell therapy in the U.S. A little over a year ago, Mike Berry of Kingston, Ont., started having trouble breathing.

http://ift.tt/1snLFb0?

Cancer-killing cells made in lab

Source: Brain tumours are often solid and hard to reach so stem cells are an effective way of targeting them. This photo is taken from BBC Online Scientists from Harvard Medical School have discovered a way of turning stem cells into killing machines to fight brain cancer.

http://ift.tt/1oKgX13

Benchmark proposed to better replicate natural stem cell development in the laboratory environment

... artificial environment, UCLA researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research led by Dr. Guoping Fan, professor of human genetics, have established a benchmarking standard to assess how culture ...

http://ift.tt/1zaE9c8

Toxin-secreting stem cells treat brain tumors, in mice

A new way to use stem cells in the fight against brain cancer has been devised by researchers. A team led by a neuroscientist who recently demonstrated the value of stem cells loaded with cancer-killing herpes viruses now has a way to genetically engineer stem cells so that they can produce and secrete tumor-killing toxins.

http://ift.tt/ZQkuPt

Indian-American Discovers Stem Cells to Kill Brain Cancer

In a breakthrough, a team of Harvard scientists led by an Indian-American researcher has discovered a novel way to fight deadly brain cancer with toxin-resistant stem cells. Harvard Stem Cell Institute scientists at Massachusetts General Hospital led by Dr Khalid Shah, who hails from Kashmir, experimented on mice and used genetically engineered stem cells that released cancer-killing toxins while leaving healthy cells unaffected.

http://ift.tt/1oJsWvQ

Science Weekly : Skin cells reprogrammed into brain cells

Huntington's disease is a disorder in which nerve cells in certain parts of the brain degenerate. This disorder is passed down through families due to a genetic defect on chromosome 4. This defect causes part of DNA called a CAG repeat to occur more times than it's supposed to.

http://ift.tt/1xq2bvI

View video in new page

A Harvard University Research Team created genetically engineered stem cells that are able to kill cancer cells, while leaving other cells unharmed. Video provided by Newsy Researchers at the Mayo Clinic are preparing to test their theory that stem cells grow faster in microgravity.

http://ift.tt/1yAkvn1

Human skin cells reprogrammed directly into brain cells

Scientists have described a way to convert human skin cells directly into a specific type of brain cell affected by Huntington's disease, an ultimately fatal neurodegenerative disorder. Unlike other techniques that turn one cell type into another, this new process does not pass through a stem cell phase, avoiding the production of multiple cell types, report researchers.

http://ift.tt/1tpmjAa

Stem Cell Transplant

A stem cell transplant - also called a blood or marrow transplant - is the injection or infusion of healthy stem cells into your body to replace damaged or diseased stem cells. A stem cell transplant may be necessary if your bone marrow stops working and doesn't produce enough healthy stem cells.

http://ift.tt/1DNrOuk

Coast Lines, Oct. 26, 2014: Santa Cruz to re-examine downtown display rules

The Santa Cruz City Council will gather Tuesday to look at a host of plans, including proposed changes to rules governing spaces downtown where people can perform or table with a display device. The changes, recommended by Vice Mayor Don Lane, Councilwoman Pamela Comstock and staff call for 60 delineated spaces where expression activities and street performance can take place with a display device, which includes a collection box for money.

http://ift.tt/1yzYVyT

Scientists at Harvard have developed a stem cell that kills cancer

... toxin. According to BBC , the treatment is getting excited responses from many in the fields of stem cell research and cancer treatment . Nell Barrie, senior science information manager for Cancer Research UK, called the treatment an "ingenious ...

http://ift.tt/1xpm6L4

Bone marrow donors sought for Groton man with lymphoma

A bone marrow drive will take place from 2 p.m. to 5:30 p.m. on Tuesday at the Groton Municipal Building to try save the life of Mark Grabherr, a wastewater treatment plant operator and lifelong resident of Groton. Grabherr, who graduated from Fitch High School in 1983, has faced life-threatening illness three times.

http://ift.tt/1ztlwBA

How a paralysed man walked again

FIRST STEPS: Darek Fidyka walks with the aid of leg-braces and a walking frame at the Akron Neuro-Rehabilitation Center in Wroclaw, Poland. A paralysed man has begun to walk again after pioneering surgery injected cells from his nasal cavity into his spine.

http://ift.tt/1toPvXV

Bone Marrow Derived Stem Cells Treatment against Low Vision

PRLog - Oct. 25, 2014 - METUCHEN, N.J. -- Helpussee helps people who are suffering from severe eye diseases. It helps people to struggle against low vision problem.

http://ift.tt/1z8EqfQ

China to open commercial animal cloning facility for mass production

... and was sentenced to two years in prison, suspended. He lost his license, disallowing him to practice stem cell research. Now, with the help of public support, Hwang is back to working on cloning animals using the somatic cell nuclear transfer ...

http://ift.tt/1wxrtI4

New Blood Vessel Grows In 1 Week When Using Stem Cells In 2 Tablespoons Of Blood

A few years ago, the idea of growing human organs in a petri dish could have incited a laugh. But labs across the world have now given shape to this idea; researchers at Sahlgrenska Academy of the University of Gothenburg have revolutionized the way new tissue can be created with stem cells.

http://ift.tt/1DMq0lx

Cloning whistleblower: Little changed in S. Korea

In this Sept. 5, 2014, Ryu Young-joon holds a container that stores human tissue and other human biological samples at a biobank during an interview at Kangwon National University Hospital in Cuncheon, South Korea.

http://ift.tt/ZO9zWy

UC San Diego Sanford Stem Cell Clinical Center named new 'alpha clinic'

... accomplish." The alpha clinic grant reflects continued CIRM support for UC San Diego's well-established stem cell research and development programs. Since it was created in 2004, CIRM has approved 74 awards totaling almost $156 million to UC San ...

http://ift.tt/1DLxF3f

PARK2 patient neuroprogenitors show increased mitochondrial sensitivity to copper.

Poorly-defined interactions between environmental and genetic risk factors underlie Parkinson's disease etiology. Here we tested the hypothesis that human stem cell derived forebrain neuroprogenitors from patients with known familial risk for early onset PD will exhibit enhanced sensitivity to PD environmental risk factors compared to healthy control subjects without a family history of PD.

http://ift.tt/1rz8KZj

Stem cells that can kill cancer have been engineered by scientists

Note: We do not store your email address but your IP address will be logged to prevent abuse of this feature. Please read our Legal Terms & Policies The team of scientists, who experimented on mice, used genetically engineered stem cells that released cancer killing toxins, while leaving healthy cells unaffected.

http://ift.tt/1tT1Jcc

Mum sets up fund to research into daughter's rare condition

For five years Zoe Crowson has devoted her time entirely to looking after her little girl who was born with the rare genetic skin condition Recessive Dystrophic Epidermolosis Bullosa or EB. Now with Phoebe, five, at school, although not yet full time, has decided to use her skills to start her own charity - The Phoebe Research Fund - to raise money for research into her daughter's condition.

http://ift.tt/1wq1rKh

Five scientists nab awards for high-risk, high-return research

The NIH has announced that Sean Wu will receive a Pioneer Award; Michael Bassik will receive a New Innovator Award; and David Chan, Michael Angelo and Eric Nelson will receive Early Independence Awards. Five scientists at the School of Medicine have received awards totaling $7.75 million to pursue high-risk, high-reward research, the National Institutes of Health announced today.

http://ift.tt/1s5cd6J

Scientists engineer toxin-secreting stem cells to treat brain tumors

Harvard Stem Cell Institute scientists at Massachusetts General Hospital have devised a new way to use stem cells in the fight against brain cancer. A team led by neuroscientist Khalid Shah, MS, PhD, who recently demonstrated the value of stem cells loaded with cancer-killing herpes viruses, now has a way to genetically engineer stem cells so that they can produce and secrete tumor-killing toxins.

http://ift.tt/1wpzFxv

The American Academy of Anti-Aging Medicine (A4M) Announces Specialty ...

The American Academy of Anti-Aging Medicine Announces Specialty Conference Workshops taking place in conjunction with the 22nd Annual World Congress on Anti-Aging Medicine in Las Vegas. The A4M will host its largest continuing medical education conference December 11-13, 2014, bringing thousands of healthcare practitioners from all specialties and corners of the world together for a dynamic, high level event featuring lectures from leading healthcare experts and practicing physicians.

http://ift.tt/1rxL07C

$8 million grant going to UCI, UCLA for stem cell trials

An $8 million grant will help researchers at UC Irvine and UCLA find ways to treat several diseases using stem cells. "We're excited about it," said Sid Golub, director of UCI's Sue and Bill Gross Stem Cell Research Center.

http://ift.tt/1zqpIlz

Anti-Cancer Drug Effective Against Common Stem Cell Transplant Complication

Researchers at UC Davis have found that the drug bortezomib effectively treats chronic graft-versus-host disease , a common and debilitating side effect from allogeneic hematopoietic stem cell transplants. The trial showed that bortezomib provides better outcomes than existing treatments and does not impair the immune response against residual cancer cells, or the graft-versus-tumor effect .

http://ift.tt/1tya5DT

New engineering method shows promise for faster healing, more cosmetically appealing skin grafts

... significantly advancing the clinical utilization of stem cell molecular and cellular biology. By bridging stem cell research and clinical trials, SCTM will help move applications of these critical investigations closer to accepted best practices. ...

http://ift.tt/1ywc3oB

UCLA and UCI awarded $8 million grant to launch collaborative stem cell clinic

The UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and UC Irvine Sue and Bill Gross Stem Cell Research Center received a five-year $8 million grant from the California Institute of Regenerative Medicine, the state's stem cell agency, to establish a CIRM Alpha Stem Cell Clinic "center of excellence" to conduct clinical trials for investigational stem cell therapies and provide critical resources and expertise in clinical research. The grant was one of three awarded this week as part of the CIRM Alpha Stem Cell Clinics Network Initiative.

http://ift.tt/12tFAVO

Cancer-killing cells made in the lab

Scientists from Harvard Medical School have discovered a way of turning stem cells into killing machines to fight brain cancer. In experiments on mice, the stem cells were genetically engineered to produce and secrete toxins which kill brain tumours, without killing normal cells or themselves.

http://ift.tt/1rvMnnx

Stem Cells Loaded With Toxins Successfully Eliminate Traces Of Brain Cancer In Mice

If stem cells are technically capable of converting into any cell, then what's stopping them from becoming poison-packing cancer-killing super cells? That was the exact thought of a group of Harvard scientists who successfully engineered stem cells that can produce and secrete a toxin capable of killing brain tumors. In the study , now published in STEM CELLS , Dr. Khalid Shah and his Harvard team described their journey to the creation of this one-of-a-kind stem cell.

http://ift.tt/12t1hVO

UCLA Scientists Propose Benchmark to Better Replicate Natural Stem...

In a study that will provide the foundation for scientists to better replicate natural stem cell development in an artificial environment, UCLA researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research led by Dr. Guoping Fan, professor of human genetics, have established a benchmarking standard to assess how culture conditions used to procure stem cells in the lab compare to those found in the human embryo. Pluripotent stem cells are cells that can transform into almost any cell in the human body.

http://ift.tt/1DJm58U

New engineering method shows promise for faster healing, more cosmetically appealing skin grafts

... significantly advancing the clinical utilization of stem cell molecular and cellular biology. By bridging stem cell research and clinical trials, SCTM will help move applications of these critical investigations closer to accepted best practices. ...

http://ift.tt/ZMyTvU

Rare disease doesn't stop former Coppell volleyball star Mikayla Bass' spirit

Mikayla "Bear" Bass with some of her medals, photographed October 17, 2014. She was a star athlete in Coppell before being diagnosed with Myasthenia Gravis.

http://ift.tt/1sZ0BQC

Verastem, Inc. Presents New Data On Mesothelioma Programs At The 12th Meeting

Professor Raphael Bueno, M.D., Chief of Thoracic Surgery, Brigham and Women's Hospital , Boston and Principal Investigator of Verastem's ongoing Window of Opportunity study presented preliminary clinical results in an oral presentation. The study is evaluating the biomarker response to VS-6063 , an oral small molecule that targets cancer stem cells through the inhibition of focal adhesion kinase in patients with resectable pleural mesothelioma.

http://ift.tt/1twrUmY

Skin Cells Reprogrammed Into Brain Cells

Image Caption: Human skin cells can be converted into medium spiny neurons with exposure to the right combination of microRNAs and transcription factors, according to work by Andrew Yoo and his research team. Credit: Yoo Lab Scientists have described a way to convert human skin cells directly into a specific type of brain cell affected by Huntington's disease , an ultimately fatal neurodegenerative disorder.

http://ift.tt/1tuVyZT

Global Stem Cells Group Names Biomen S.a as exclusive Representative in Costa Rica

... Cells Group, Inc. is the parent company of six wholly owned operating companies dedicated entirely to stem cell research, training, products and solutions. Founded in 2012, the company combines dedicated researchers, physician and patient educators ...

http://ift.tt/1pIJzCY

The answer was under his nose

Science often turns on serendipity. Breakthroughs have emerged from a whimsical fascination with folklore ; from the accidental contamination of an experiment ; and from the unexpected side-effects of drugs .

http://ift.tt/1uQD3LT

Doctors Use Adult (Not Embryonic) Stem Cells To Grow And Implant Petri-Dish Retina

... of research at Toronto's Hospital for Sick Children and past president of the International Society for Stem Cell Research. The Riken Center for Developmental Biology has also been in the news lately because its deputy director committed suicide ...

http://ift.tt/1xibaiq

Scientists Convert Human Skin Cells Into Brain Cells

For the first time, scientists have converted human skin cells directly into a type of brain cell affected by Huntington's disease, a fatal inherited neurological disorder. The new technique is different from other methods that turn one type of cell into another because it bypasses the stem cell phase.

http://www.newsmax.com/Health-News/Huntingtons-brain-disease-skin-cells/2014/10/24/id/602889/

MIT researchers develop new way to model effects of cancer-causing genetic mutations

Sequencing the genomes of tumor cells has revealed thousands of genetic mutations linked with cancer. However, sifting through this deluge of information to figure out which of these mutations actually drive cancer growth has proven to be a tedious, time-consuming process.

http://ift.tt/1woRASr

Growing a blood vessel in a week

... ... DefiniGEN is one of the first commercial opportunities to arise from Cambridge's expertise in stem cell research. Here, we look at some of the fundamental research that enables it to supply liver and pancreatic ... A hormone seen as a popular ...

http://ift.tt/1pHTKrg

Scientists engineer toxin-secreting stem cells to treat brain tumors

Encapsulated toxin-producing stem cells help kill brain tumor cells in the tumor resection cavity . Credit: Khalid Shah, MS, PhD Harvard Stem Cell Institute scientists at Massachusetts General Hospital have devised a new way to use stem cells in the fight against brain cancer.

http://ift.tt/1z4C0Pp

National Stem Cell Foundation Release: Stem Cell And Orthopaedic...

The collaboration between NSCF and OREF will allow both organizations to focus on stem cell research expected to play a key role in the future of orthopaedic medicine.The collaboration between NSCF and OREF will allow both organizations to focus on stem cell research which is expected to play a key role in the future of orthopaedic medicine. According to the World Health Organization, musculoskeletal disorders resulting from injury, age or disease are the most common cause of severe long-term pain and physical disability, affecting hundreds of millions of people worldwide.

http://ift.tt/1yuotgP

Synageva BioPharma Presents Sebelipase Alfa Data At The Meeting

After completing the initial four-week portion of the trial, patients were allowed to continue treatment with sebelipase alfa as part of a long-term, open-label extension study. Eight of nine patients enrolled in the extension study and continue treatment with sebelipase alfa.

http://ift.tt/1sXTd85

Stem Cells Grown From Patient's Arm Used To Replace Retina

BarbaraHudson writes: The Globe and Mail is reporting the success of a procedure to implant a replacement retina grown from cells from the patient's skin . Quoting: "Transplant doctors are stepping gingerly into a new world, one month after a Japanese woman received the first-ever tissue transplant using stem cells that came from her own skin, not an embryo.

http://ift.tt/1wkUmui

UC San Diego Named Stem Cell "Alpha Clinic"

... accomplish." The alpha clinic grant reflects continued CIRM support for UC San Diego's well-established stem cell research and development programs. Since it was created in 2004, CIRM has approved 74 awards totaling almost $156 million to UC San ...

http://ift.tt/1pHQImR

Stem Cells Grown From Patient's Arm Used To Replace Retina

BarbaraHudson writes: The Globe and Mail is reporting the success of a procedure to implant a replacement retina grown from cells from the patient's skin . Quoting: "Transplant doctors are stepping gingerly into a new world, one month after a Japanese woman received the first-ever tissue transplant using stem cells that came from her own skin, not an embryo.

http://ift.tt/12pYlcv

Hearing the Ovarian Cancer Whisper Awards $125,000 for Ovarian Cancer Research

According to her application documentation, "Recent research supports the fallopian tube as the site of origin of serous ovarian cancer. New stem cell science has enabled never before modeling of many tissues and even organs.

http://ift.tt/1DHSA7z

Cloning whistleblower: Little changed in S. Korea

The whistleblower who exposed breakthrough cloning research as a devastating fake says South Korea is still dominated by the values that allowed science fraudster Hwang Woo-suk to become an almost untouchable national hero. In an interview with The Associated Press after almost a decade of silence, Ryu Young-joon, one of Hwang's former researchers, said the cost of telling the truth still weighs on him but he doesn't regret his decision to out Hwang as a false prophet.

http://ift.tt/12pKnYj

Cloning whistleblower: Little changed in S. Korea

5, 2014 photo, Ryu Young-joon speaks during an interview at Kangwon National University Hospital in Cuncheon, South Korea. . In this Sept.

http://ift.tt/ZLA5Qb

Testing time for stem cells

DefiniGEN is one of the first commercial opportunities to arise from Cambridge's expertise in stem cell research. Here, we look at some of the fundamental research that enables it to supply liver and pancreatic cells for drug screening.

http://ift.tt/1oBaOEu

Stem cell and orthopaedic foundations partner on stem cell research

The collaboration between NSCF and OREF will allow both organizations to focus on stem cell research expected to play a key role in the future of orthopaedic medicine.The collaboration between NSCF and OREF will allow both organizations to focus on stem cell research which is expected to play a key role in the future of orthopaedic medicine. According to the World Health Organization, musculoskeletal disorders resulting from injury, age or disease are the most common cause of severe long-term pain and physical disability, affecting hundreds of millions of people worldwide.

http://ift.tt/1xgWQqj

Scientists convert human skin cells directly into brain cells

By exposing skin cells to a particular combination of cell programming molecules, scientists managed to convert them into brain cells that behave like native cells. Human skin cells can be converted into medium spiny neurons with exposure to the right combination of microRNAs and transcription factors, according to work by Andrew Yoo and colleagues.

http://ift.tt/1xgReMQ

Cell transplant enables paralyzed man to walk again

A new treatment has allowed Darek Fidyka to take his first steps after being paralyzed from the chest down as a result of a knife attack In 2010, Darek Fidyka was paralyzed from the chest down as a result of a knife attack that left an 8 mm gap in his spinal column. Now surgeons in Poland, working in collaboration with scientists in London, have given Fidyka the ability to walk again thanks to a new procedure using transplanted cells from his olfactory bulbs.

http://ift.tt/1tpOopN

Verastem Presents New Data on Mesothelioma Programs at the 12th...

Verastem, Inc. , focused on discovering and developing drugs to treat cancer by the targeted killing of cancer stem cells, announced the presentation of clinical and preclinical data in oral presentation and discussion sessions at the 12th International Mesothelioma Interest Group Conference being held October 22-24, 2014, at the Cape Town International Conference Centre in Cape Town, South Africa.

http://ift.tt/1D5TOHl

Fast Modeling of Cancer Mutations

Sequencing the genomes of tumor cells has revealed thousands of genetic mutations linked with cancer. However, sifting through this deluge of information to figure out which of these mutations actually drive cancer growth has proven to be a tedious, time-consuming process.

http://ift.tt/1vWwn3d

Human skin cells reprogrammed directly into brain cells

Scientists have described a way to convert human skin cells directly into a specific type of brain cell affected by Huntington's disease , an ultimately fatal neurodegenerative disorder. Unlike other techniques that turn one cell type into another, this new process does not pass through a stem cell phase, avoiding the production of multiple cell types, the study's authors report.

http://ift.tt/1wjDbt0

Human skin cells reprogrammed directly into brain cells

Summary Scientists have developed a new method to convert human skin cells directly into a specific type of brain cell... Scientists have developed a new method to convert human skin cells directly into a specific type of brain cell affected by Huntington's disease, an ultimately fatal neurodegenerative disorder. Unlike other techniques that turn one cell type into another, the new process does not pass through a stem cell phase, avoiding the production of multiple cell types, said researchers.

http://ift.tt/1tpDGiT

Human skin cells reprogrammed directly into brain cells

Scientists have described a way to convert human skin cells directly into a specific type of brain cell affected by Huntington's disease, an ultimately fatal neurodegenerative disorder. Unlike other techniques that turn one cell type into another, this new process does not pass through a stem cell phase, avoiding the production of multiple cell types, report researchers.

http://ift.tt/1sgh4vS

Stem Cell Agency Unveils CIRM 2.0 - " its Aggressive Plan to...

... The Board also voted to continue funding for another year the Creativity Awards and the CIRM Bridges to Stem Cell Research Awards programs. The Creativity program gives high school students, many from poor and low-income communities, a paid summer ...

http://ift.tt/1D5e5wE

Whistle-blower sees little change in South Korea 10 years after exposing cloning fraud

The whistle-blower who exposed breakthrough cloning research as a devastating fake says South Korea is still dominated by the values that allowed science fraudster Hwang Woo-suk to become an almost untouchable national hero. In an interview with The Associated Press after almost a decade of silence, Ryu Young-joon, one of Hwang's former researchers, said the cost of telling the truth still weighs on him but he doesn't regret his decision to out Hwang as a false prophet.

http://ift.tt/1toPMsw

Cloning whistle-blower: little change in S. Korea

The whistle-blower who exposed breakthrough cloning research as a devastating fake says South Korea is still dominated by the values that allowed science fraudster Hwang Woo-suk to become an almost untouchable national hero. In an interview with The Associated Press after almost a decade of silence, Ryu Young-joon, one of Hwang's former researchers, said the cost of telling the truth still weighs on him but he doesn't regret his decision to out Hwang as a false prophet.

http://ift.tt/1sWiBv5

Cloning whistle-blower: little change in S. Korea

5, 2014 photo, Ryu Young-joon speaks during an interview at Kangwon National University Hospital in Cuncheon, South Korea. . In this Sept.

http://ift.tt/12nt61W

visit|article-5844267|mobile_home_category_body-6916|6

The whistle-blower who exposed breakthrough cloning research as a devastating fake says South Korea is still dominated by the values that allowed science fraudster Hwang Woo-suk to become an almost untouchable national hero. In an interview with The Associated Press after almost a decade of silence, Ryu Young-joon, one of Hwang's former researchers, said the cost of telling the truth still weighs on him but he doesn't regret his decision to out Hwang as a false prophet.

http://ift.tt/1uNM34t

Cloning Whistle-Blower: Little Change in S. Korea

In this Sept. 5, 2014 photo, Ryu Young-joon speaks during an interview at Kangwon National University Hospital in Cuncheon, South Korea.

http://ift.tt/1xfRKuk

Baker, Coakley square off in Chicopee debate

... as a "classic Massachusetts Republican voting record," noting her support for abortion rights and stem cell research, among other initiatives. Coakley then shifted to Baker's tenure as the state's health and human services chief in the 1990s, when ...

http://ift.tt/1oAfdYn

UC San Diego Named Stem Cell 'Alpha Clinic'

Stanford Stem Cell Clinical Center at UC San Diego was named one of three "alpha clinics" for stem cell research; it will speed funding. In a push to further speed clinical development of emerging stem cell therapies, Sanford Stem Cell Clinical Center at UC San Diego Health System was named Thursday, Oct. 23 one of three new "alpha clinics" by the California Institute for Regenerative Medicine , the state's stem cell agency.

http://ift.tt/1DGAmDk?

How nasal cells helped a paralyzed man walk again

A man, paralyzed after being attacked with a knife, is able to walk again thanks to stem-cell research. A team of scientists from the U.K. and Poland managed to take cells from the patients nose and ankle and repair the damaged cells in his spine.

http://ift.tt/1DGAliG

UCSD, other stem cell clinics get millions

... board also approved $9 million to help train newer generations of stem scientists under its "Bridges to Stem Cell Research" program. To date, $50.6 million have been committed to the program, and the $9 million will extend it by one more year. In ...

http://ift.tt/1nB4X17

Arthur Porter, Peter Nygard and Perry Christie

TheunravellingofDr Arthur Porter's life didn't begin in the Bahamas. But it could be said to have ended here - more orless.

http://ift.tt/1z2l63X

Stem cell research helping canines

In his office at St. Francis Pet Care Center in Tarpon Springs, veterinarian Michael Amsberry is helping lead the way with stem cell research. Working with Animal Cell Therapies, a veterinary stem cell research and development company in San Diego, Amsberry is experimenting with the use of umbilical stem cells to treat canine allergic dermatitis, which typically presents as a skin rash or irritation.

http://ift.tt/1sVloEJ

Synageva BioPharma Presents Sebelipase Alfa Data At The NASPGHAN Meeting

After completing the initial four-week portion of the trial, patients were allowed to continue treatment with sebelipase alfa as part of a long-term, open-label extension study. Eight of nine patients enrolled in the extension study and continue treatment with sebelipase alfa.

http://ift.tt/1yr9x2Y

Five scientists nab awards for high-risk, high-return research

The NIH has announced that Sean Wu will receive a Pioneer Award; Michael Bassik will receive a New Innovator Award; and David Chan, Michael Angelo and Eric Nelson will receive Early Independence Awards. Five scientists at the School of Medicine have received awards totaling $7.75 million to pursue high-risk, high-reward research, the National Institutes of Health announced today.

http://ift.tt/1s5cd6J

UCLA and UCI partner for stem cell research

UCLA and UCI stem cell researchers received a five year $8 million grant from the California Institute of Regenerative Medicine On October 23, the University of California, Los Angeles Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and University of California, Irvine Sue & Bill Gross Stem Cell Research Center announced that they had received a five year $8 million grant from the California Institute of Regenerative Medicine . The CIRM, California's stem cell agency supplied the funds to establish a CIRM Alpha Stem Cell Clinic "center of excellence" to conduct clinical trials for investigational stem cell therapies and provide critical resources and expertise in clinical research.

http://ift.tt/12l8rvo

UCI Will Form Stem Cell Clinic with UCLA, Thanks to $5M Grant

... by the California Institute for Regenerative Medicine. "UCI has established a strong preclinical stem cell research program, and it's vital to move ahead to the clinical testing phase," said Sidney Golub, director of UCI's Sue & Bill Gross Stem Cell ...

http://patch.com/california/newportbeach/uci-will-form-stem-cell-clinic-ucla-thanks-5m-grant?

Scientific leader Alan Leshner encourages ethical approach to science

... increasing public support for scientific funding. However, dispute occurs over sensitive topics such as stem cell research, human sexual behavior and the causes of drug addiction. In the case of drug addiction, advances in neuroscience have ...

http://ift.tt/1FKwXFs

Stem Cell in the Rough: Repair Quotient Mined Out of a Bone Marrow Niche [Editorials]

Regenerative medicine aims to repair, replace, or restore diseased, damaged, or missing tissues. Cardiovascular indications account for over a quarter of all cell-based regenerative medicine products currently in development.

http://ift.tt/1ronf1K

Genetic causes underlying the disqualification of two elite American Standardbred pacers

A DNA mutation that can lead to horses being genetically male, but female in appearance, may explain at least two cases of controversial sexual identity, according to research led by professors from the Texas A&M College of Veterinary Medicine & Biomedical Sciences and published in PLOS Genetics . This type of genetic abnormality is caused by a mutation called DNA copy number variation , in which there are deletions and duplications in the genome typically larger than 50 base pairs.

http://ift.tt/1sUjgwY

UCLA and UCI Awarded $8M Grant to Launch Collaborative Stem Cell Clinic "Center of Excellence"

In a first-of-its-kind collaboration, the University of California, Los Angeles, Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research and University of California, Irvine Sue & Bill Gross Stem Cell Research Center received a five year $8M grant from the California Institute of Regenerative Medicine , the state's stem cell agency, to establish a CIRM Alpha Stem Cell Clinic "center of excellence" to conduct clinical trials for investigational stem cell therapies and provide critical resources and expertise in clinical research. The $8M grant was one of three awarded today by CIRM as part of the CIRM Alpha Stem Cell Clinics Network Initiative.

http://www.newswise.com/articles/view/625126/?sc=rssn&utm_source=feedburner&utm_medium=feed&utm_campaign=Feed%3A+NewswiseScinews+%28Newswise%3A+SciNews%29

Successful retina transplant sparks hope

... at the Hospital for Sick Children in Toronto and the past president of the International Society for Stem Cell Research. The Japanese woman is fine and her retinal implant remains in place. Researchers around the world are now hoping to test other ...

http://ift.tt/1DFaA2f

A Scalable Approach for Discovering Conserved Active Subnetworks across Species

Overlaying differential changes in gene expression on protein interaction networks has proven to be a useful approach to interpreting the cell's dynamic response to a changing environment. Despite successes in finding active subnetworks in the context of a single species, the idea of overlaying lists of differentially expressed genes on networks has not yet been extended to support the analysis of multiple species' interaction networks.

http://www.citeulike.org/user/chasmand/article/8403801

Environment Could Improve Stem Cell Therapies

Stem cell therapies are being hailed as a potential cure for many major health conditions, but there is much still to learn about the highly complex environments needed to optimize these therapies, according to researchers at the University of Adelaide. For her Ph.D. in the University's School of Medicine, Sarah Hemming is studying the complex non-genetic factors that help to turn normal stem cells into bone-making cells.

http://ift.tt/1zmvsN1

Gene that once aided survival in the Arctic found to have negative impact on health today

In individuals living in the Arctic, researchers have discovered a genetic variant that arose thousands of years ago and most likely provided an evolutionary advantage for processing high-fat diets or for surviving in a cold environment; however, the variant also seems to increase the risk of hypoglycemia, or low blood sugar, and infant mortality in today's northern populations. The findings, published online October 23 in Cell Press's American Journal of Human Genetics , provide an example of how an initially beneficial genetic change could be detrimental to future generations.

http://ift.tt/1DEEvHR